Diet.

I am on a strict diet. I have actually never been on a diet like this, so this is completely new for me. I have always done some form of exercise to stay in good shape.

I do not know. But there is something with the food I buy. I get very dizzy.

I believe all humans need some kind of reward. I usually reward myself with some sweets. Right now, I find it very difficult not having any reward at all. I have to learn my brain not to be so found of sweets. And I have to find new rewards. That is why I love photos. Sweet Lady and Tippa. For example.

Alcohol interferes with brain reward systems in a very complex way. And what is important for us women is to really be aware of that Alcohol eg increases the risk of breast cancer. It also reduces the responsiveness of your immune system. But maybe most important, regular alcohol intake can lead to dependence.

I am really scared that it is not mentioned in the debate today that when youngsters are exposed to a drug, the risk of being more sensitive to another drug increases dramatically. So, for society in general, it is very dangerous to have a drug liberal politic. Politicians believe that they know what is right without having a solid ground.

I don´t know how many times I need to repeat that politicians need to learn biology. Maybe I need to learn more politics 😉

I will soon write more about brain reward systems. I am just not ready yet.

 

Je t’embrasse,

Anna

Is it ethical to change history?

It seems like I will never get rid of my previous boyfriends and friends actions.  I do not know what I can do about it. As I have written previously, I have tried to live my life as ethical as possible. Unfortunately, I am too naive sometimes. And too faithful. I should underline that I am a nun today.

I am not gay. I do not have anything against homosexuality. As I have written before, it is very important to have a biological variance. That is, it is good to have a large biological variety. For mankind.

You should not force nature, but rather, try to follow the laws of nature and live in harmony.

Last night. I faced and realized evil. How someone wish my life to fade away. I got afraid. It has still not reached my consciousness. I do not know if I can handle that feeling. I rarely get afraid. Personal development. How to handle evil. Should you hit back? Is that a good solution?

Blame. If people could take personal responsibility over their actions, the world would become better. In psychology, projection, is an explanation over certain behavior. To further explain, if you get angry over something you know you have caused yourself, you blame somebody else. To find a peaceful solution is to reflect over your actions. Ethical responsibility.

I like the photo a lot I published yesterday. For me it represents freedom. It is also the name of my mother. Elsa. She has been rather strict in raising me and my brother, but she has always taken good care of us. Even though her memory is not the best to date, she always talks about my brother. Since I have had it easier at school, she cares more about my brother since he is more vulnerable. Every family has their own privacy and I would like to keep it that way.

Somehow, it is a special day today. I follow the news about what’s happening in Russia-Krim. I hope people will not be harmed and that politicians talk instead of using weapons. Good leadership, according to me, is to talk, and talk, and talk. If leaders don’t dare to say what they wish then evil has gained ground. I fight evil.

 

Je t’embrasse,

Anna

 

 

Today.

Just relaxing today. A grey day in Stockholm so not much to do but to enjoy life as much as possible. It also is the 1st of March. Amazing how time passes. I think quite a lot of time. How memories fade away, giving place to new memories. Also called positive thinking.

You might have noticed that I like photos. And walks. I try to catch moments of life when I see them. This photo above is from a previous walk. Isn’t it beautiful? There are many boats in Stockholm and that is good because it revives my memories from living in Göteborg. I miss the fresh seafood and salt water from the west coast. However, still on a diet.

Today is a go with the flow day.

Je t’embrasse,

Anna

PS. Still problems with photos, not in the position I would like.

 

 

 

Every day is unique

It is really nice to have a diary. Since I write directly on the internet I don’t have to think about hiding my writing. I have had trubble with someone breaking into my apartment. Not so nice. But I know that I am not alone of this so that comforts me. It scares me that our community is turning into an unsafe world. What are the signals for future generations?

Violence generates violence.

My philosophy is to have my own gard and if somebody is not nice to me then I have to do something about the situation. I think a lot of people have seen what’s happening in the USA. Media plays an important role in augmenting dangerous situations.

What makes me a bit fuzzy is that some people seek conflicts instead of thinking of how to make something good out of a situations. There will always be conflicts between people. That is for sure. But since we have this knowledge, we also have a possibility to avoid conflicts and make good solutions.

Mostly, from my point of view, is to use your brain. Yes, everybody has a brain. Again, I would like to mention Professor Arvid Carlsson talking about the reptile brain. The brain has developed throughout ages. I said it before, I believe the impulse controlling systems in the brain are very important. They help you to manage your fear, anger etc. However, when you meet somebody who do not have their feelings under control then it gets complicated.

I need to elaborate on this but this is extremely important if you would like to stay in balance with your feelings and importantly your relations.

Personally, I am at a time point in my life where I have to look after myself. I have been hurt by so many people. So I am very careful. I think everybody who has been hurt also knows how difficult it is to face similar situations. That is to get out of your comfort zone.

I am grown up in the countryside. I have always known that I have been adopted and later, I learnt a little about my “indian” background. But the life I know is only the country side. Please, try to understand that.

Sweet dreams,

Anna

 

Uppsala.

Since I don´t have any statistics I don´t know if there is anyone reading this. Today I bought a new computer because I write so much. And I use the freedom of internet.

I have thought a lot about what I wrote last time. It is a summary of a pharmacological Cinderella fairytale. I love pharmacology. I have always been interested in pharmacology and I will see how I can continue to contribute.

I have had problems with the internet today. Hackers probably. Scary.

Since I have a new computer I have to upload old photos etc. I bumped into this photo. If you ever go to Sweden you can see this photo on a 100 SEK bill. It is a beautiful garden with many medical plants. Nice cafe as well.

Since I am single, I just cannot stay at home. You have to expose yourself to new situations and environments. I feel sorry for being single. But there has to be a man out there for me.

I think of all my sisters going through the same journey as I do. Dating. Bad guys. Not being serious.

I have to wait for a long time.

Meanwhile I have to enjoy myself in the very best way I can. It is very boring to be alone. Waste of time. But what do you do. No choices. So, sisters. I know what it is like. And don’t forget to wait for a nice man you love. And maybe, most importantly, a man who loves you.

Je t’embrasse,

Anna

 

Repetition är pedagogikens moder.

VARDAGSFILOSOFI MED DEXTER & LAEVO
Det här skrev jag på FB för ungefär ett år sedan.
Jag skriver inte om vänster och höger ur politisk synvinkel utan ifrån en biologisk grund. Tror att de biologiska marknadskrafterna är svåra att förstå sig på.

Jag har under många år haft (och har fortfarande)ett stort intresse av biologi och särskilt farmakologi. Det är nu flera år sedan jag studerade men jag följer med i tidningar och populärvetenskaplig litteratur.

Om jag skulle återuppta vetenskap igen så skulle jag vilja se närmare på varför det finns enantiomerer. Alltså, det är samma kemiska substans men de är varandras spegelbilder. Ungefär som vänster och höger hand. De ser lika ut men om man lägger den ena handen över den andra så är de ju inte lika. L(A)EVO och DEXTER. I Frankrike, för några decennier sedan, så skakades landet av Thalidomid skandalen. Det var just den ena av enantiomeren som visade sig vara teratogen.

Ett annat exempel är Losec®. Där är ju omeprazol den aktiva substansen. Låt säga att det motsvarar vänster hand. Under senare år så har en vidareutveckling skett där man “renat” fram “höger hand”. Höger hand motsvarar här esomeprazol (Nexium®). Det är många patienter som upplever att den ena enantiomeren fungerar bättre än den andra enantiomeren.

Framtagandet av esomeprazol/omeprazol är en farmakologisk framgångs saga. Det är verkligen äkta forskning. Jag skulle kunna hålla en hel föreläsning i ämnet. Att förstå att magbesvär kan orsakas av en bakteri (helocobacter pylori) var vid den tiden svår att förstå. Det forskaren gjorde var att, helt enkelt, dricka bakterier för att se om det gav besvär. Kopplingen att en bakterie kunde påverka magsyrebalans var svår att förstå. Framtagandet av omeprazol gjordes i ett nära samarbete mellan universitet och industri i Göteborg-Mölndal. Här spelade Ivan Östholm en avgörande roll. För den intresserade så finns det litteratur om honom. Han var, kan man säga, medlare mellan akademi och industri. Ungefär den roll som Jan Eliasson har i FN. För att göra någon form av begriplig jämförelse.

Den kliniska relevansen av framtagandet av Losec® är oerhört stor. Tidigare var man tvungen att genomföra ganska avancerade kirurgiska ingrepp. Samhället i dess helhet har sparat oerhört mycket pengar på introducerandet av omeprazol. Dessa kostnader är svåra att mäta men är av oerhört stor signifikans ur en ekonomisk-biologisk-human synvinkel.

Inte att förglömma är dos-respons viktigt. Vissa människor behöver högre dos än andra för att uppnå en kliniskt relevant effekt.

Det verkar som om att en enantiomer fungerar bättre som läkemedel hos vissa människor, medan den andra enantiomeren kan visa bättre effekt hos andra. Ibland kan det bli sidoeffekter. Varför är det så? Vad händer om det blir obalans i kroppen, alltså mer av den ena enantiomeren? Har många frågor jag skulle vilja få svar på.

Den här boken fick jag i disputationspresent av min handledare Professor Jörgen Engel. Jag är oerhört tacksam att jag fick en forskarutbildning med frihet under ansvar. Det var verkligen så. Och jag har författat min avhandling själv som jag än idag försvarar.

Verkar som om hackers fortfarande har sportlov. Dessvärre. Bilderna som jag publicerar är ej i det format jag önskar.

Ha en fin helg!